ea0049ep1449 | Thyroid (non-cancer) | ECE2017
Tavares Catarina
, Coelho Maria Joao
, Eloy Catarina
, Melo Miguel
, da Rocha Adriana Gaspar
, Pestana Ana
, Batista Rui
, Ferreira Luciana Bueno
, Rios Elisabete
, Cavadas Bruno
, Pereira Luisa
, Selmi-Ruby Samia
, Simoes Manuel Sobrinho
, Soares Paula
Thyroid cancer therapy is based on surgery followed by radioiodine treatment of tumor remnants and metastases. The incorporation of radioiodine by cancer cells is mediated by sodium iodide symporter (NIS), normally present in thyroid follicular cellsÂ’ membrane. We studied the expression of NIS in a series of 229 thyroid primary tumors using real time PCR and immunohistochemistry, and searched for possible associations between NIS expression and clinicopathological feature...